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Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells

Liver transplantation is the definitive treatment of liver failure but donor organ shortage limits its availability. Stem cells are highly expandable and have the potential to differentiate into any specialist cell. Use of patient-derived induced Pluripotent Stem Cells (hiPSCs) has the additional ad...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lorvellec, Maëlle, Scottoni, Federico, Crowley, Claire, Fiadeiro, Rebeca, Maghsoudlou, Panagiotis, Pellegata, Alessandro Filippo, Mazzacuva, Francesca, Gjinovci, Asllan, Lyne, Anne-Marie, Zulini, Justine, Little, Daniel, Mosaku, Olukunbi, Kelly, Deirdre, De Coppi, Paolo, Gissen, Paul
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738056/
https://ncbi.nlm.nih.gov/pubmed/29261712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189586
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