Vps33b is crucial for structural and functional hepatocyte polarity

BACKGROUND & AIMS: In the normal liver, hepatocytes form a uniquely polarised cell layer that enables movement of solutes from sinusoidal blood to canalicular bile. Whilst several cholestatic liver diseases with defects of hepatocyte polarity have been identified, the molecular mechanisms of pat...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Hanley, Joanna, Dhar, Dipok Kumar, Mazzacuva, Francesca, Fiadeiro, Rebeca, Burden, Jemima J., Lyne, Anne-Marie, Smith, Holly, Straatman-Iwanowska, Anna, Banushi, Blerida, Virasami, Alex, Mills, Kevin, Lemaigre, Frédéric P., Knisely, A.S., Howe, Steven, Sebire, Neil, Waddington, Simon N., Paulusma, Coen C., Clayton, Peter, Gissen, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387182/
https://ncbi.nlm.nih.gov/pubmed/28082148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2017.01.001
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