Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7

PURPOSE: To test the genetic association between Japanese patients with primary open-angle glaucoma (POAG) and the previously reported POAG susceptibility loci and to perform genotype–phenotype analysis. METHODS: Genetic associations for 27 SNPs from 16 loci previously linked to POAG were assessed u...

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Pubblicato in:PLoS One
Autori principali: Shiga, Yukihiro, Nishiguchi, Koji M., Kawai, Yosuke, Kojima, Kaname, Sato, Kota, Fujita, Kosuke, Takahashi, Mai, Omodaka, Kazuko, Araie, Makoto, Kashiwagi, Kenji, Aihara, Makoto, Iwata, Takeshi, Mabuchi, Fumihiko, Takamoto, Mitsuko, Ozaki, Mineo, Kawase, Kazuhide, Fuse, Nobuo, Yamamoto, Masayuki, Yasuda, Jun, Nagasaki, Masao, Nakazawa, Toru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737967/
https://ncbi.nlm.nih.gov/pubmed/29261660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186678
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