Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7

PURPOSE: To test the genetic association between Japanese patients with primary open-angle glaucoma (POAG) and the previously reported POAG susceptibility loci and to perform genotype–phenotype analysis. METHODS: Genetic associations for 27 SNPs from 16 loci previously linked to POAG were assessed u...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shiga, Yukihiro, Nishiguchi, Koji M., Kawai, Yosuke, Kojima, Kaname, Sato, Kota, Fujita, Kosuke, Takahashi, Mai, Omodaka, Kazuko, Araie, Makoto, Kashiwagi, Kenji, Aihara, Makoto, Iwata, Takeshi, Mabuchi, Fumihiko, Takamoto, Mitsuko, Ozaki, Mineo, Kawase, Kazuhide, Fuse, Nobuo, Yamamoto, Masayuki, Yasuda, Jun, Nagasaki, Masao, Nakazawa, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737967/
https://ncbi.nlm.nih.gov/pubmed/29261660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186678
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