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Combining in Vitro and in Silico Single-Molecule Force Spectroscopy to Characterize and Tune Cellulosomal Scaffoldin Mechanics

Cellulosomes are poly-protein machineries that efficiently degrade cellulosic material. Crucial to their function are scaffolds consisting of highly homologous cohesin domains, which serve a dual role by coordinating a multiplicity of enzymes as well as anchoring the microbe to its substrate. Here w...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Verdorfer, Tobias, Bernardi, Rafael C, Meinhold, Aylin, Ott, Wolfgang, Luthey-Schulten, Zaida, Nash, Michael A, Gaub, Hermann E
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737924/
https://ncbi.nlm.nih.gov/pubmed/29058444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07574
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