Naturally existing isoforms of miR-222 have distinct functions

Deep-sequencing reveals extensive variation in the sequence of endogenously expressed microRNAs (termed ‘isomiRs’) in human cell lines and tissues, especially in relation to the 3′ end. From the immunoprecipitation of the microRNA-binding protein Argonaute and the sequencing of associated small RNAs...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yu, Feng, Pillman, Katherine A., Neilsen, Corine T., Toubia, John, Lawrence, David M., Tsykin, Anna, Gantier, Michael P., Callen, David F., Goodall, Gregory J., Bracken, Cameron P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737821/
https://ncbi.nlm.nih.gov/pubmed/28981911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx788
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