Affinity States of Striatal Dopamine D2 Receptors in Antipsychotic-Free Patients with Schizophrenia

BACKGROUND: Dopamine D2 receptors are reported to have high-affinity (D2(High)) and low-affinity (D2(Low)) states. Although an increased proportion of D2(High) has been demonstrated in animal models of schizophrenia, few clinical studies have investigated this alteration of D2(High) in schizophrenia...

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Udgivet i:Int J Neuropsychopharmacol
Main Authors: Kubota, Manabu, Nagashima, Tomohisa, Takano, Harumasa, Kodaka, Fumitoshi, Fujiwara, Hironobu, Takahata, Keisuke, Moriguchi, Sho, Kimura, Yasuyuki, Higuchi, Makoto, Okubo, Yoshiro, Takahashi, Hidehiko, Ito, Hiroshi, Suhara, Tetsuya
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Regular Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737675/
https://ncbi.nlm.nih.gov/pubmed/29016872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx063
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