Inhibition of HDAC3 prevents diabetic cardiomyopathy in OVE26 mice via epigenetic regulation of DUSP5-ERK1/2 pathway

Inhibition of total histone deacetylases (HDACs) was phenomenally associated with the prevention of diabetic cardiomyopathy (DCM). However, which specific HDAC plays the key role in DCM remains unclear. The present study was designed to determine whether DCM can be prevented by specific inhibition o...

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Detalhes bibliográficos
Publicado no:Clin Sci (Lond)
Main Authors: Xu, Zheng, Tong, Qian, Zhang, Zhiguo, Wang, Shudong, Zheng, Yang, Liu, Qiuju, Qian, Lingbo, Chen, Shao-yu, Sun, Jian, Cai, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737625/
https://ncbi.nlm.nih.gov/pubmed/28533215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20170064
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