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Diabetic Cardiomyopathy in OVE26 Mice Shows Mitochondrial ROS Production and Divergence Between In Vivo and In Vitro Contractility

Many diabetic patients suffer from a cardiomyopathy that cannot be explained solely by poor coronary perfusion. This cardiomyopathy may be due to either organ-based damage like fibrosis, or to direct damage to cardiomyocytes. Mitochondrial-derived reactive oxygen species (ROS) have been proposed to...

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Detalhes bibliográficos
Main Authors: Song, Ye, Du, Yibo, Prabhu, Sumanth D., Epstein, Paul N.
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174063/
https://ncbi.nlm.nih.gov/pubmed/18084673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2007.4.159
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