Correlation of immune phenotype with IDH mutation in diffuse glioma

BACKGROUND: Tumor infiltrating lymphocytes (TILs) and programmed death ligand 1 (PD-L1) are targets of immune checkpoint inhibitors. METHODS: Forty-three World Health Organization (WHO) grade II/III gliomas (39 IDH-mutant [mut], 4 IDH-wildtype [wt]) and 14 IDH-mut glioblastomas (GBM) were analyzed f...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Berghoff, Anna Sophie, Kiesel, Barbara, Widhalm, Georg, Wilhelm, Dorothee, Rajky, Orsolya, Kurscheid, Sebastian, Kresl, Philip, Wöhrer, Adelheid, Marosi, Christine, Hegi, Monika E, Preusser, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737620/
https://ncbi.nlm.nih.gov/pubmed/28531337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox054
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