Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma

BACKGROUND: Immune checkpoint inhibitors targeting programmed cell death 1 (PD1) or its ligand (PD-L1) showed activity in several cancer types. METHODS: We performed immunohistochemistry for CD3, CD8, CD20, HLA-DR, phosphatase and tensin homolog (PTEN), PD-1, and PD-L1 and pyrosequencing for assessm...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Berghoff, Anna Sophie, Kiesel, Barbara, Widhalm, Georg, Rajky, Orsolya, Ricken, Gerda, Wöhrer, Adelheid, Dieckmann, Karin, Filipits, Martin, Brandstetter, Anita, Weller, Michael, Kurscheid, Sebastian, Hegi, Monika E., Zielinski, Christoph C., Marosi, Christine, Hainfellner, Johannes A., Preusser, Matthias, Wick, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490866/
https://ncbi.nlm.nih.gov/pubmed/25355681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou307
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