Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma

BACKGROUND: Immune checkpoint inhibitors targeting programmed cell death 1 (PD1) or its ligand (PD-L1) showed activity in several cancer types. METHODS: We performed immunohistochemistry for CD3, CD8, CD20, HLA-DR, phosphatase and tensin homolog (PTEN), PD-1, and PD-L1 and pyrosequencing for assessm...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Berghoff, Anna Sophie, Kiesel, Barbara, Widhalm, Georg, Rajky, Orsolya, Ricken, Gerda, Wöhrer, Adelheid, Dieckmann, Karin, Filipits, Martin, Brandstetter, Anita, Weller, Michael, Kurscheid, Sebastian, Hegi, Monika E., Zielinski, Christoph C., Marosi, Christine, Hainfellner, Johannes A., Preusser, Matthias, Wick, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490866/
https://ncbi.nlm.nih.gov/pubmed/25355681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou307
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