A deep boosting based approach for capturing the sequence binding preferences of RNA-binding proteins from high-throughput CLIP-seq data

Characterizing the binding behaviors of RNA-binding proteins (RBPs) is important for understanding their functional roles in gene expression regulation. However, current high-throughput experimental methods for identifying RBP targets, such as CLIP-seq and RNAcompete, usually suffer from the false n...

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Bibliografiske detaljer
Udgivet i:	Nucleic Acids Res
Main Authors:	Li, Shuya, Dong, Fanghong, Wu, Yuexin, Zhang, Sai, Zhang, Chen, Liu, Xiao, Jiang, Tao, Zeng, Jianyang
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2017
Fag:	Methods Online
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5737578/ https://ncbi.nlm.nih.gov/pubmed/28575488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx492
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A deep boosting based approach for capturing the sequence binding preferences of RNA-binding proteins from high-throughput CLIP-seq data

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