Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions

Chromatin recruitment of effector proteins involved in gene regulation depends on multivalent interaction with histone post-translational modifications (PTMs) and structural features of the chromatin fiber. Due to the complex interactions involved, it is currently not understood how effectors dynami...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bryan, Louise C., Weilandt, Daniel R., Bachmann, Andreas L., Kilic, Sinan, Lechner, Carolin C., Odermatt, Pascal D., Fantner, Georg E., Georgeon, Sandrine, Hantschel, Oliver, Hatzimanikatis, Vassily, Fierz, Beat
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737501/
https://ncbi.nlm.nih.gov/pubmed/28985346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx697
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