De novo genome assembly of Camptotheca acuminata, a natural source of the anti-cancer compound camptothecin

Camptotheca acuminata is 1 of a limited number of species that produce camptothecin, a pentacyclic quinoline alkaloid with anti-cancer activity due to its ability to inhibit DNA topoisomerase. While transcriptome studies have been performed previously with various camptothecin-producing species, no...

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Bibliographic Details
Published in:Gigascience
Main Authors: Zhao, Dongyan, Hamilton, John P., Pham, Gina M., Crisovan, Emily, Wiegert-Rininger, Krystle, Vaillancourt, Brieanne, DellaPenna, Dean, Buell, C. Robin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737489/
https://ncbi.nlm.nih.gov/pubmed/28922823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/gix065
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