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Gene-regulatory interactions in embryonic stem cells represent cell-type specific gene regulatory programs

Pluripotency, the ability of embryonic stem cells to differentiate into specialized cell types, is determined by ESC-specific gene regulators such as transcription factors and chromatin modification factors. It is not well understood how ESCs are poised for differentiation, however, and methods are...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ha, Misook, Hong, Soondo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737473/
https://ncbi.nlm.nih.gov/pubmed/28977540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx752
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