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Role of DNA polymerase β oxidized nucleotide insertion in DNA ligation failure
Production of reactive oxygen and nitrogen species (ROS), such as hydrogen peroxide, superoxide and hydroxyl radicals, has been linked to cancer, and these oxidative molecules can damage DNA. Base excision repair (BER), a major repair system maintaining genome stability over a lifespan, has an impor...
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| Pubblicato in: | J Radiat Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737452/ https://ncbi.nlm.nih.gov/pubmed/28992331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrx027 |
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