Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes

Although epidermal keratinocyte development and differentiation proceeds in similar fashion between humans and mice, evolutionary pressures have also wrought significant species-specific physiological differences. These differences between species could arise in part, by the rewiring of regulatory n...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Sethi, Isha, Gluck, Christian, Zhou, Huiqing, Buck, Michael J., Sinha, Satrajit
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737389/
https://ncbi.nlm.nih.gov/pubmed/28505376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx416
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