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Multiplexed analysis of fixed tissue RNA using Ligation in situ Hybridization

Clinical tissues are prepared for histological analysis and long-term storage via formalin fixation and paraffin embedding (FFPE). The FFPE process results in fragmentation and chemical modification of RNA, rendering it less suitable for analysis by techniques that rely on reverse transcription (RT)...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Credle, Joel J., Itoh, Christopher Y., Yuan, Tiezheng, Sharma, Rajni, Scott, Erick R., Workman, Rachael E., Fan, Yunfan, Housseau, Franck, Llosa, Nicolas J., Bell, W. Robert., Miller, Heather, Zhang, Sean X., Timp, Winston, Larman, H. Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737328/
https://ncbi.nlm.nih.gov/pubmed/28854731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx471
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