H2B ubiquitylation and the histone chaperone Asf1 cooperatively mediate the formation and maintenance of heterochromatin silencing

Heterochromatin is a heritable form of gene repression, with critical roles in development and cell identity. Understanding how chromatin factors results in such repression is a fundamental question. Chromatin is assembled and disassembled during transcription, replication and repair by anti-silenci...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Wu, Meng-Ying, Lin, Chia-Yeh, Tseng, Hsin-Yi, Hsu, Fei-Man, Chen, Pao-Yang, Kao, Cheng-Fu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737242/
https://ncbi.nlm.nih.gov/pubmed/28520954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx422
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