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Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei

Antigenic variation in African trypanosomes involves monoallelic expression and reversible silencing of variant surface glycoprotein (VSG) genes found adjacent to telomeres in polycistronic expression sites (ESs). We assessed the impact on ES silencing of five candidate essential chromatin-associate...

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Detalhes bibliográficos
Main Authors: Alsford, Sam, Horn, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488249/
https://ncbi.nlm.nih.gov/pubmed/22941664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks813
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