Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality

Biologically functional DNA hairpins are found in archaea, prokaryotes and eukaryotes, playing essential roles in various DNA transactions. However, during DNA replication, hairpin formation can stall the polymerase and is therefore prevented by the single-stranded DNA binding protein (SSB). Here, w...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Grieb, Maj Svea, Nivina, Aleksandra, Cheeseman, Bevan L., Hartmann, Andreas, Mazel, Didier, Schlierf, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737091/
https://ncbi.nlm.nih.gov/pubmed/28985409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx670
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