Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality

Biologically functional DNA hairpins are found in archaea, prokaryotes and eukaryotes, playing essential roles in various DNA transactions. However, during DNA replication, hairpin formation can stall the polymerase and is therefore prevented by the single-stranded DNA binding protein (SSB). Here, w...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Grieb, Maj Svea, Nivina, Aleksandra, Cheeseman, Bevan L., Hartmann, Andreas, Mazel, Didier, Schlierf, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737091/
https://ncbi.nlm.nih.gov/pubmed/28985409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx670
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