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Xylopine Induces Oxidative Stress and Causes G(2)/M Phase Arrest, Triggering Caspase-Mediated Apoptosis by p53-Independent Pathway in HCT116 Cells
Xylopine is an aporphine alkaloid that has cytotoxic activity to cancer cells. In this study, the underlying mechanism of xylopine cytotoxicity was assessed in human colon carcinoma HCT116 cells. Xylopine displayed potent cytotoxicity in different cancer cell lines in monolayer cultures and in a 3D...
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| Publicat a: | Oxid Med Cell Longev |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736936/ https://ncbi.nlm.nih.gov/pubmed/29362667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7126872 |
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