A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells

Stathmin/Oncoprotein 18, a microtubule destabilizing protein, is required for survival of p53-deficient cells. Stathmin-depleted cells are slower to enter mitosis, but whether delayed mitotic entry triggers cell death or whether stathmin has a separate pro-survival function was unknown. To test thes...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Silva, Victoria C, Plooster, Melissa, Leung, Jessica C, Cassimeris, Lynne
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612104/
https://ncbi.nlm.nih.gov/pubmed/25602147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1007781
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