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Factor Xa inhibition by rivaroxaban in the trough steady state can significantly reduce thrombin generation
AIMS: The aim of the present study was to demonstrate evidence of reduced thrombin generation at the trough plasma rivaroxaban concentration. METHODS: A single‐centre, prospective, nonrandomized, drug‐intervention, self‐controlled study was conducted in 51 anticoagulation therapy‐naïve patients with...
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| Veröffentlicht in: | Br J Clin Pharmacol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736851/ https://ncbi.nlm.nih.gov/pubmed/28888219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13429 |
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