Brucella abortus Promotes a Fibrotic Phenotype in Hepatic Stellate Cells, with Concomitant Activation of the Autophagy Pathway

The liver is frequently affected in patients with active brucellosis. The present study demonstrates that Brucella abortus infection induces the activation of the autophagic pathway in hepatic stellate cells to create a microenvironment that promotes a profibrogenic phenotype through the induction o...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Arriola Benitez, Paula Constanza, Pesce Viglietti, Ayelén Ivana, Herrmann, Claudia Karina, Dennis, Vida A., Comerci, Diego José, Giambartolomei, Guillermo Hernán, Delpino, María Victoria
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736806/
https://ncbi.nlm.nih.gov/pubmed/28993461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00522-17
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