Leishmania-Derived Trimannose Modulates the Inflammatory Response To Significantly Reduce Leishmania major-Induced Lesions

Leishmania lipophosphoglycan (LPG) is a key virulence factor, initiating inflammation resulting in cutaneous lesions. LPG is capped by various oligosaccharides. How these glycans are recognized and how they alter the course of Leishmania infection are poorly understood. Previous studies synthesized...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Grinnage-Pulley, Tara L., Kabotso, Daniel E. K., Rintelmann, Chelsea L., Roychoudhury, Rajarshi, Schaut, Robert G., Toepp, Angela J., Gibson-Corley, Katherine N., Parrish, Molly, Pohl, Nicola L. B., Petersen, Christine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736800/
https://ncbi.nlm.nih.gov/pubmed/29061708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00672-17
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