Leishmania-Derived Trimannose Modulates the Inflammatory Response To Significantly Reduce Leishmania major-Induced Lesions

Leishmania lipophosphoglycan (LPG) is a key virulence factor, initiating inflammation resulting in cutaneous lesions. LPG is capped by various oligosaccharides. How these glycans are recognized and how they alter the course of Leishmania infection are poorly understood. Previous studies synthesized...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Grinnage-Pulley, Tara L., Kabotso, Daniel E. K., Rintelmann, Chelsea L., Roychoudhury, Rajarshi, Schaut, Robert G., Toepp, Angela J., Gibson-Corley, Katherine N., Parrish, Molly, Pohl, Nicola L. B., Petersen, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736800/
https://ncbi.nlm.nih.gov/pubmed/29061708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00672-17
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