Leishmania-Derived Trimannose Modulates the Inflammatory Response To Significantly Reduce Leishmania major-Induced Lesions

Leishmania lipophosphoglycan (LPG) is a key virulence factor, initiating inflammation resulting in cutaneous lesions. LPG is capped by various oligosaccharides. How these glycans are recognized and how they alter the course of Leishmania infection are poorly understood. Previous studies synthesized...

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Vydáno v:Infect Immun
Hlavní autoři: Grinnage-Pulley, Tara L., Kabotso, Daniel E. K., Rintelmann, Chelsea L., Roychoudhury, Rajarshi, Schaut, Robert G., Toepp, Angela J., Gibson-Corley, Katherine N., Parrish, Molly, Pohl, Nicola L. B., Petersen, Christine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736800/
https://ncbi.nlm.nih.gov/pubmed/29061708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00672-17
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