Leishmania-Derived Trimannose Modulates the Inflammatory Response To Significantly Reduce Leishmania major-Induced Lesions

Leishmania lipophosphoglycan (LPG) is a key virulence factor, initiating inflammation resulting in cutaneous lesions. LPG is capped by various oligosaccharides. How these glycans are recognized and how they alter the course of Leishmania infection are poorly understood. Previous studies synthesized...

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發表在:Infect Immun
Main Authors: Grinnage-Pulley, Tara L., Kabotso, Daniel E. K., Rintelmann, Chelsea L., Roychoudhury, Rajarshi, Schaut, Robert G., Toepp, Angela J., Gibson-Corley, Katherine N., Parrish, Molly, Pohl, Nicola L. B., Petersen, Christine A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2017
主題:
Fungal and Parasitic Infections
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736800/
https://ncbi.nlm.nih.gov/pubmed/29061708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00672-17
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