Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue

PURPOSE: Polyamidoamine (PAMAM) dendrimers are a promising class of nanocarrier with applications in both small and large molecule drug delivery. Here we report a comprehensive evaluation of the uptake and transport pathways that contribute to the lung disposition of dendrimers. METHODS: Anionic PAM...

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Vydáno v:Pharm Res
Hlavní autoři: Morris, Christopher J., Aljayyoussi, Ghaith, Mansour, Omar, Griffiths, Peter, Gumbleton, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736778/
https://ncbi.nlm.nih.gov/pubmed/28616685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2190-7
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