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Uptake, Efflux, and Mass Transfer Coefficient of Fluorescent PAMAM Dendrimers into Pancreatic Cancer Cells

Targeted delivery of imaging agents to cells can be optimized with the understanding of uptake and efflux rates. Cellular uptake of macromolecules is studied frequently with fluorescent probes. We hypothesized that the internalization and efflux of fluorescently labeled macromolecules into and out o...

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Detalhes bibliográficos
Main Authors: Opitz, Armin W., Czymmek, Kirk J., Wickstrom, Eric, Wagner, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534946/
https://ncbi.nlm.nih.gov/pubmed/23022133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.09.016
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