The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) represents a fatal orphan disease with high unmet medical need, and a life time risk of approx. 1/400 persons per population. Based on increasing knowledge on pathophysiology including genetic and molecular changes, epigenetics, and immune dysfunction, inflammator...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Peters, Sebastian, Zitzelsperger, Eva, Kuespert, Sabrina, Iberl, Sabine, Heydn, Rosmarie, Johannesen, Siw, Petri, Susanne, Aigner, Ludwig, Thal, Dietmar R., Hermann, Andreas, Weishaupt, Jochen H., Bruun, Tim-Henrik, Bogdahn, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736544/
https://ncbi.nlm.nih.gov/pubmed/29326641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00669
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