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Co-treatment with a C1B5 peptide of protein kinase Cγ and a low dose of gemcitabine strongly attenuated pancreatic cancer growth in mice through T cell activation

Although gemcitabine is an effective chemotherapeutic for pancreatic cancer, severe side effects often accompany its use. Since we have discovered that locally administered C1B domain peptides effectively control tumor growth without any side effects, the efficacy of co-treatment with this peptide a...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Ishiguro, Susumu, Kawabata, Atsushi, Zulbaran-Rojas, Alejandro, Monson, Kelsey, Uppalapati, Deepthi, Ohta, Naomi, Inui, Makoto, Pappas, Charalampos G., Tzakos, Andreas G., Tamura, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736436/
https://ncbi.nlm.nih.gov/pubmed/29155177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.11.102
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