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Identification of ATIC as a novel target for chemoradiosensitization
PURPOSE: Mutations in the gene encoding 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), a bifunctional enzyme that catalyzes the final two steps of the purine de novo biosynthetic pathway, were identified in a subject referred for radiation sensitivity test...
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| Publicado no: | Int J Radiat Oncol Biol Phys |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736427/ https://ncbi.nlm.nih.gov/pubmed/29029884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2017.08.033 |
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