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Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells

PURPOSE: Corneal basement membrane has topographical features that provide biophysical cues to direct cell adherence, migration, and proliferation. In this study, we hypothesize that varying topographic pitch created on silk films can alter epithelial cell morphology, adhesion, and the genetic expre...

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Detalles Bibliográficos
Publicado en:Invest Ophthalmol Vis Sci
Main Authors: Kang, Kai B., Lawrence, Brian D., Gao, X. Raymond, Luo, Yuncin, Zhou, Qiang, Liu, Aihong, Guaiquil, Victor H., Rosenblatt, Mark I.
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736325/
https://ncbi.nlm.nih.gov/pubmed/29260198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22213
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