Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells

PURPOSE: Corneal basement membrane has topographical features that provide biophysical cues to direct cell adherence, migration, and proliferation. In this study, we hypothesize that varying topographic pitch created on silk films can alter epithelial cell morphology, adhesion, and the genetic expre...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kang, Kai B., Lawrence, Brian D., Gao, X. Raymond, Luo, Yuncin, Zhou, Qiang, Liu, Aihong, Guaiquil, Victor H., Rosenblatt, Mark I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Cornea
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736325/
https://ncbi.nlm.nih.gov/pubmed/29260198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22213
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