Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration

Adult mammalian cardiomyocyte regeneration after injury is thought to be minimal. Mononuclear diploid cardiomyocytes (MNDCMs), a relatively small subpopulation in the adult heart, may account for the observed degree of regeneration, but this has not been tested. We surveyed 120 inbred mouse strains...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Patterson, Michaela, Barske, Lindsey, Van Handel, Ben, Rau, Christoph D, Gan, Peiheng, Sharma, Avneesh, Parikh, Shan, Denholtz, Matt, Huang, Ying, Yamaguchi, Yukiko, Shen, Hua, Allayee, Hooman, Crump, J Gage, Force, Thomas I, Lien, Ching-Ling, Makita, Takako, Lusis, Aldons J, Kumar, S Ram, Sucov, Henry M
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736145/
https://ncbi.nlm.nih.gov/pubmed/28783163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3929
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