Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling

Injury to the newborn mouse heart is efficiently regenerated, but this capacity is lost by one week after birth. We found that IGF2, an important mitogen in heart development, is required for neonatal heart regeneration. IGF2 originates from the endocardium/endothelium and is transduced in cardiomyo...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Shen, Hua, Gan, Peiheng, Wang, Kristy, Darehzereshki, Ali, Wang, Kai, Kumar, S Ram, Lien, Ching-Ling, Patterson, Michaela, Tao, Ge, Sucov, Henry M
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105374/
https://ncbi.nlm.nih.gov/pubmed/32167474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53071
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki