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Cytoplasmic domain effects on exposure of co-receptor-binding sites of HIV-1 Env

We defined the effects of the cytoplasmic domain (CT) of the Env glycoprotein on co-receptor usage of HIV-1 by reciprocal exchanges of regions containing V3–V5 loops between CD4-dependent and CD4-independent isolates. Primary HIV-1 isolate Env clones CD8 CXCR4-tropic 92UG046 CT84 with an 84-aa trunc...

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Foilsithe in:Arch Virol
Main Authors: Vzorov, Andrei N., Compans, Richard W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736137/
https://ncbi.nlm.nih.gov/pubmed/27488878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-016-2998-1
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