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Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells

Chromosome conformation capture (3C) techniques are crucial to understanding tissue-specific regulation of gene expression, but current methods generally require large numbers of cells. This protocol describes two new low-input Capture-C approaches that can generate high-quality 3C interaction profi...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Oudelaar, Marieke A., Downes, Damien J., Davies, James O.J., Hughes, Jim R.
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736099/
https://ncbi.nlm.nih.gov/pubmed/29270442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2645
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