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Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes
We report a novel delivery platform for a highly potent anticancer drug, 7-(benzylamino)-3,4-dihydro-pyrrolo[4,3,2-de]quinolin-8(1H)-one (BA-TPQ), using pH- and redox-sensitive poly(methacrylic acid) (PMAA) hydrogel cubes of micrometer size as the encapsulating matrix. The hydrogels are obtained upo...
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| Publicado no: | Acta Biomater |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736006/ https://ncbi.nlm.nih.gov/pubmed/28583901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.06.004 |
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