Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes

We report a novel delivery platform for a highly potent anticancer drug, 7-(benzylamino)-3,4-dihydro-pyrrolo[4,3,2-de]quinolin-8(1H)-one (BA-TPQ), using pH- and redox-sensitive poly(methacrylic acid) (PMAA) hydrogel cubes of micrometer size as the encapsulating matrix. The hydrogels are obtained upo...

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Detaylı Bibliyografya
Yayımlandı:Acta Biomater
Asıl Yazarlar: Xue, Bing, Wang, Wei, Qin, Jiang-Jiang, Nijampatnam, Bhavitavya, Murugesan, Srinivasan, Kozlovskaya, Veronika, Zhang, Ruiwen, Velu, Sadanandan E., Kharlampieva, Eugenia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736006/
https://ncbi.nlm.nih.gov/pubmed/28583901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.06.004
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