Effects of Shizhifang on NLRP3 Inflammasome Activation and Renal Tubular Injury in Hyperuricemic Rats

OBJECTIVE: Uric acid (UA) activates the NLRP3-ASC-caspase-1 axis and triggers cascade inflammatory that leads to hyperuricemic nephropathy and hyperuricemia-induced renal tubular injury. The original study aims to verify the positive effects of the traditional Chinese medicinal formula Shizhifang (S...

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Bibliographic Details
Published in:Evid Based Complement Alternat Med
Main Authors: Wu, Yansheng, He, Fei, Li, Yingqiao, Wang, Huiling, Shi, Liqiang, Wan, Qiang, Ou, Jiaoying, Zhang, Xiaoying, Huang, Di, Xu, Lin, Lin, Pinglan, Yang, Guanghui, He, Liqun, Gao, Jiandong
Format: Artigo
Language:Inglês
Published: Hindawi 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735790/
https://ncbi.nlm.nih.gov/pubmed/29358971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7674240
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