Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling

OBJECTIVE: We previously reported that dexmedetomidine (DEX) offers cardioprotection against ischemia/reperfusion injury in rats. Here, we evaluated the role of toll-like receptors 4- (TLR4-) myeloid differentiation primary response 88- (MyD88-) nuclear factor-kappa B (NF-κB) signaling in DEX-mediat...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Gao, Jin-meng, Meng, Xiao-wen, Zhang, Juan, Chen, Wei-rong, Xia, Fan, Peng, Ke, Ji, Fu-hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735617/
https://ncbi.nlm.nih.gov/pubmed/29359143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1674613
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