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The Evaluation of Pharmacodynamics and Pharmacokinetics of Anti-thrombin DNA Aptamer RA-36

Anticoagulants are a vital class of drugs, which are applied for short-term surgical procedures, and for long-term treatments for thrombosis prevention in high risk groups. Several anticoagulant drugs are commercially available, but all have intrinsic disadvantages, e.g., bleeding risks, as well as...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Zavyalova, Elena, Samoylenkova, Nadezhda, Revishchin, Alexander, Turashev, Askar, Gordeychuk, Ilya, Golovin, Andrey, Kopylov, Alexey, Pavlova, Galina
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735248/
https://ncbi.nlm.nih.gov/pubmed/29311929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00922
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