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Covalent Bi-Modular Parallel and Antiparallel G-Quadruplex DNA Nanocostructs Reduce Viability of Patient Glioma Primary Cell Cultures

G-quadruplex oligonucleotides (GQs) exhibit specific anti-proliferative activity in human cancer cell lines, and they can selectively inhibit the viability/proliferation of cancer cell lines vs. non-cancer ones. This ability could be translated into a cancer treatment, in particular for glioblastoma...

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Publicat a:Int J Mol Sci
Autors principals: Legatova, Valeria, Samoylenkova, Nadezhda, Arutyunyan, Alexander, Tashlitsky, Vadim, Zavyalova, Elena, Usachev, Dmitry, Pavlova, Galina, Kopylov, Alexey
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036578/
https://ncbi.nlm.nih.gov/pubmed/33806042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073372
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