N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy

Mechanisms underlying the renal pathology in cardiorenal syndrome (CRS) type 2 remain elusive. We hypothesised that renal glutathione deficiency is central to the development of CRS type 2. Glutathione precursor, N-acetylcysteine (NAC;40 mg/kg/day; 8 weeks) or saline were administered to transgenic...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Giam, Beverly, Kuruppu, Sanjaya, Chu, Po-Yin, Smith, A. Ian, Marques, Francine Z., Fiedler, April, Horlock, Duncan, Kiriazis, Helen, Du, Xiao-Jun, Kaye, David M., Rajapakse, Niwanthi W.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735149/
https://ncbi.nlm.nih.gov/pubmed/29255249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17927-5
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