Identification of Potential MHC Class-II-Restricted Epitopes Derived from Leishmania donovani Antigens by Reverse Vaccinology and Evaluation of Their CD4+ T-Cell Responsiveness against Visceral Leishmaniasis

Visceral leishmaniasis (VL) is one of the most neglected tropical diseases for which no vaccine exists. In spite of extensive efforts, no successful vaccine is available against this dreadful infectious disease. To support vaccine development, an immunoinformatics approach was applied to screen pote...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Dikhit, Manas Ranjan, Kumar, Akhilesh, Das, Sushmita, Dehury, Budheswar, Rout, Ajaya Kumar, Jamal, Fauzia, Sahoo, Ganesh Chandra, Topno, Roshan Kamal, Pandey, Krishna, Das, V. N. R., Bimal, Sanjiva, Das, Pradeep
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735068/
https://ncbi.nlm.nih.gov/pubmed/29312304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01763
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