The potential HLA Class I-restricted epitopes derived from LeIF and TSA of Leishmania donovani evoke anti-leishmania CD8+ T lymphocyte response

To explore new protective measure against visceral leishmaniasis, reverse vaccinology approach was employed to identify key immunogenic regions which can mediate long-term immunity. In-depth computational analysis revealed nine promiscuous epitopes which can possibly be presented by 46 human leukocy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dikhit, Manas Ranjan, Das, Sushmita, Mahantesh, Vijaya, Kumar, Akhilesh, Singh, Ashish Kumar, Dehury, Budheswar, Rout, Ajaya Kumar, Ali, Vahab, Sahoo, Ganesh Chandra, Topno, Roshan Kamal, Pandey, Krishna, Das, V. N. R., Bimal, Sanjiva, Das, Pradeep
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154976/
https://ncbi.nlm.nih.gov/pubmed/30242172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32040-x
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