Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma

Radiation therapy has been long utilized as localized cancer treatment. Recent studies have also demonstrated that it has a distant effect by the enhanced immunity, but it rarely occurs. The purpose of this study was to investigate whether X-ray irradiation combined with anti-PD-L1 and anti-CTLA-4 a...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Takahashi, Yutaka, Yasui, Tomohiro, Tamari, Keisuke, Minami, Kazumasa, Otani, Keisuke, Isohashi, Fumiaki, Seo, Yuji, Kambe, Ryosuke, Koizumi, Masahiko, Ogawa, Kazuhiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734786/
https://ncbi.nlm.nih.gov/pubmed/29253865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189697
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