Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma

Carbon ion radiotherapy has been utilized even for X-ray resistant tumors. However, control of distant metastasis remains a major challenge in carbon ion irradiation. We investigated whether carbon ion irradiation combined with dual immune checkpoint blockade therapy (anti-PD-L1 and anti-CTLA-4 anti...

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Vydáno v:Oncotarget
Hlavní autoři: Takahashi, Yutaka, Yasui, Tomohiro, Minami, Kazumasa, Tamari, Keisuke, Hayashi, Kazuhiko, Otani, Keisuke, Seo, Yuji, Isohashi, Fumiaki, Koizumi, Masahiko, Ogawa, Kazuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363009/
https://ncbi.nlm.nih.gov/pubmed/30774761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26551
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